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Aldevron to generate antibodies for erythropoietin research consortium
Aldevron, a leader in the field of genetic immunisation, will apply its proprietary GENOVAC Antibody Technology to develop sets of monoclonal antibodies against the erythropoietin receptor (EpoR) for different applications, including antibodies capable of detecting EpoRs in its native conformation in tumour samples and the ability to modulate the function of this receptor.
Dr. John Thompson of Aldevron, a pioneer in the genetic immunisation technology to be deployed, noted that GENOVAC Antibody Technology is uniquely suited to provide antibodies to the EPO research consortium and is pleased to produce "antibodies that could further be developed as therapeutic drugs for certain indications."
The research consortia, called EPOCAN, plans to implement a comprehensive interdisciplinary strategy to identify and alleviate the risks involved in treatment with erythropoietin (EPO) and its derivatives (epoetins) in cancer patients and those with chronic kidney disease. It is estimated that up to one million patients across Europe and North America receive epoetin treatment each year.
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