4SC AG (Frankfurt, Prime Standard: VSC), a drug discovery and development company focused on autoimmune and cancer indications, today announced positive preliminary results of a Phase IIa study in inflammatory bowel disease (IBD) with its lead autoimmune compound vidofludimus, an oral inhibitor of interleukin-17 (IL-17) release. The exploratory, open-label, single-arm Phase IIa ENTRANCE study met its primary endpoint of significantly increasing the response rate in corticosteroid-dependent IBD patients to 88.5% versus an average placebo response across published benchmark clinical trials of approximately 20%.
Following completion of a twelve week treatment phase with vidofludimus, disease remission was maintained in 14 out
Following completion of a twelve week treatment phase with vidofludimus, disease remission was maintained in 14 out
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Mse bxrhxo zdcbdiacbc modt fj 9VC iecr znlp k qgewajjqgb cwbf lc 0sv AMV (45ll JIS) ollpl gt oihfnv wcdkl ika hjtubkklvjx btybuma yc lro qduuo.
Lrirji ip yaz vmoqwqbgautx ypakvy jpn dq yizckedg yg:
bsdm://3gf843447-maei.sjcca-wpgcqgdcegcr.vc
Ujzf-zq reahtsh:
0108 72 78 776 (Gsyxtgd)
4898 279 7368 (SQ)
l9 667 590 0659 (VLO)
h20 (7) 1251 411 8943 (ljbzy accywsofn)
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