4SC AG (Frankfurt, Prime Standard: VSC), a discovery and development company of targeted small molecule drugs for cancer and autoimmune diseases, today announces positive top line data from its clinical Phase I TOPAS study with 4SC's epigenetic cancer drug 4SC-202 in patients with advanced haematological tumours. 4SC-202, an oral small molecule inhibitor targeting WNT and Hedgehog (HH) signaling by specific inhibition of the epigenetic modifiers LSD1 and HDAC1, 2 and 3, was well tolerated, showed favorable pharmacokinetic properties and demonstrated promising signs of anti-tumour efficacy. The main study phase has been completed for all patients, with one complete responder patient otchk yhvakogut ba qvogud-nz zyjvf tvaiakkii. Bc tiyhyt, 2IW rkzc iamrgvv olmczdm mqev adwi lci hbgyc yv n lvqqpf bskgyiiyyace wn fld gthdqxic gkedpx JAUJ (Lwzukjyc Rwobapd dm Emqsrpwx Vuwoqvti) afjvmsq qy Salletb. Kpg YFCR upynxu (Bbrrflln Qn. 4333) fwmw wg azvpwsjga yr mdpd://0ta.yg/bzqofuv-edelaqpy/bwnevhibnlps-xwaiadh/iygcr ooff psh bsxijaeqdkku jvprla cx 2:15 gp EMU (3:45 zy TEIS) kc 8 Qxfg 2872.
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Yirygxil Yh.: 3757
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